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Libtayo (cemiplimab-rwlc) is used to treat metastatic cutaneous squamous cell carcinoma, basal cell carcinoma, and non-small cell lung cancer. Includes Libtayo side effects, interactions and indications. Cemiplimab-rwlc is a type of monoclonal antibody therapy, which works to stimulate the immune system to destroy cancer cells. Cemiplimab-rwlc works as a form of immunotherapy by binding to the “programmed death receptor” (PD1) found on T-cells to stimulate the immune system to find and kill cancer cells. Pembrolizumab and cemiplimab have been approved as treatment for advanced non-small-cell lung cancer (NSCLC) with high programmed death ligand-1 (PD-L1) expression. This study aimed to evaluate the cost-effectiveness of pembrolizumab compared with. Libtayo is an immunotherapy drug approved for certain skin and lung cancers. Learn how it works, what conditions it treats, and what to expect during treatment. THE FOOD AND DRUG ADMINISTRATION (FDA) approved the immunotherapy Libtayo (cemiplimab) for high-risk cutaneous squamous-cell carcinoma (CSCC), a common skin cancer type. The Oct. 8, 2025, approval was based on findings that people given Libtayo after surgery and radiation lived longer without their disease recurring—a measure known as disease-free survival—compared with those treated with. This article is about Cemiplimab-rwlc (Libtayo), its uses, side effects, dosage, and what to expect during treatment. Cemiplimab-rwlc is a type of drug called an immune checkpoint inhibitor (a type of immunotherapy). It is a monoclonal antibody that binds to the protein PD-1 on the surface of immune cells called T cells. It works by keeping cancer cells from suppressing the immune system. This allows the immune system to attack and kill the cancer cells. Cemiplimab (Libtayo) Cemiplimab is a monoclonal antibody. It stimulates the immune system to attack cancer cells. It is a treatment for advanced cutaneous squamous cell carcinoma (SCC). 1.3 Non-Small Cell Lung Cancer LIBTAYO in combination with platinum-based chemotherapy is indicated for the first-line treatment of adult patients with non-small cell lung cancer (NSCLC) with no EGFR, ALK or ROS1 aberrations and is: LIBTAYO is a prescription medicine used to treat adults with a type of skin cancer called basal cell carcinoma (BCC) when your BCC cannot be removed by surgery (locally advanced BCC) or when it has spread (metastatic BCC) and have previously received treatment with a hedgehog pathway inhibitor (HHI), or cannot receive treatment with a HHI.