Seroquel overdose
Know the warning signs, management, and treatment of a Seroquel overdose. Learn about proper medication dosing to facilitate optimal healthcare. An overdose of Seroquel can lead to severe complications, including central nervous system depression, sinus tachycardia, delirium and even death. Keep reading to learn about the symptoms, emergency response, and preventive measures to avoid taking too much Seroquel. Quetiapine is an atypical antipsychotic, being an antagonist of serotonin and to a lesser extent, dopaminergic, histaminic, muscarinic and peripheral alpha 1 adrenoreceptors. Though it is frequently involved in poisonings, the evidence for paediatric poisonings is scant and case based. Here, we present the first case report of an intoxication with an extreme overdose of quetiapine (36 g), ingested by a 32-year-old female (62 kg bodyweight) to attempt suicide. Taking too much Seroquel can lead to an overdose. Not everyone who takes too much Seroquel experiences symptoms of an overdose, and the amount required to overdose varies from person to person. Seroquel is an atypical antipsychotic medication that can be lethal in very high doses, or when mixed with other drugs. Adverse side effects of Seroquel toxicity include kidney failure, hyperglycemia, diabetic coma, and death. Learn about how much Seroquel may result in a fatal overdose, what happens during a Seroquel overdose, and how to help a person who has taken too much. Quetiapine antagonises the mesolimbic dopamine (D2), serotonin, histamine the muscarninic M1 and peripheral alpha 1 receptors. This causes an anticholinergic effect (muscarinic receptors) in overdose and drowsiness (histamine receptor blockade). Discussions of the clinical use of these drugs, details concerning potential side effects, and general management of drug overdose are found elsewhere. (See General approach to drug poisoning in adults.) All quetiapine overdose patients requiring hospitalization must be admitted to an intensive care unit. 2 Continue close medical supervision and monitoring until the patient fully recovers, which may take 2-3 days for cardiovascular effects (tachycardia, QTc prolongation) even in uncomplicated cases. 1, 2.