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In its Q2 earnings call Thursday, Novartis said it is moving quickly to reshore its drug manufacturing operations, but CEO Vas Narasimhan told reporters that for most medicines, it typically takes three to four years to completely relocate production. Amid an outpouring of pharma investment dollars into China, Novartis is the latest multinational drugmaker lining up to bolster its research and production operations in the country. The Swiss pharma will collectively invest more than 3.3 billion Chinese yuan (roughly $480 million) to soup up. Pancreatic cancer has produced a fair number of blow-ups, with Erytech’s Graspa and Rafael’s devimistat recently joining a long list of clinical failures. But several new therapies have entered late-stage trials since Evaluate Vantage last looked at the pipeline. Novartis is making a big push here, recently starting a phase 3 trial of its anti-TGF-β MAb NIS793; the Swiss group yesterday. Novartis nabbed FDA approval for Kesimpta to treat multiple sclerosis last year, but now it’s getting the thumbs-up from MS patients and nurses. Novartis presented study data at the sixth annual Americas Committee for Treatment and Research in Multiple Sclerosis Forum in late February showing 84% preferred Kesimpta’s self-administration injector pen over rival administration methods. Novartis will have to wait a little longer to see if the U.S. Food and Drug Administration (FDA) will greenlight Arzerra (ofatumumab) as a treatment for patients with relapsing multiple sclerosis (RMS). On Tuesday, the FDA extended its review of the Supplemental Biologics License Application for Arzerra in this indication by three months. Regulatory action is now expected in September 2020. Novartis unveils North Carolina API plant as final piece of $23B US expansion BioSpace Friday, May 1, 2026 - 11:31 am Novartis, North Carolina, drug manufacturing Anonymous board for Novartis. The deal cycle is heating up, with pharma gearing up for a big M&A year, while earnings, IPOs and regulatory shifts fill out the rest. Big Pharma M&A set for mega year as patent expiries drive deal urgency Pharma/Biotech General Discussion board Moderna tops revenue estimates on stronger international COVID vaccine sales Moderna board Repatha sales help Amgen overcome Prolia biosimilar hits in. Xolair, a 20-year-old asthma drug sold by Roche (ROG.S) and Novartis (NOVN.S) significantly reduced allergic reactions in people with multiple severe food allergies in a late-stage trial, researchers reported on Sunday at a medical meeting. Novartis has netted a pair of regulatory wins, winning European approval for an oral therapy in chronic spontaneous urticaria (CSU) and, separately, receiving World Health Organization (WHO) prequalification for its antimalarial medication.

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