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Easy-to-read patient leaflet for Effexor. Includes indications, proper use, special instructions, precautions, and possible side effects. Serotonin syndrome is a serious drug reaction. It is caused by medications that build up high levels of serotonin in the body. Serotonin is a chemical that the body produces naturally. It's needed for the nerve cells and brain to function. But too much serotonin causes signs and symptoms that can range from mild (shivering and diarrhea) to severe (muscle rigidity, fever and seizures). Severe. Sexual side effects are common with antidepressants in both men and women, but there are options to prevent or reduce such side effects. Antidepressants are a popular treatment choice for depression. Although antidepressants may not cure depression, they can reduce symptoms. The first antidepressant you try may work fine. But if it doesn't relieve your symptoms or it causes side effects that bother you, you may need to try another. Learn about the side effects of Effexor XR (venlafaxine), from common to rare, for consumers and healthcare professionals. Serotonin and norepinephrine reuptake inhibitors, also called SNRIs, are a class of medicines that are effective in treating depression. They also are sometimes used to treat other conditions, such as anxiety and long-term pain, especially nerve pain. SNRIs may be helpful if you have both long-term pain and depression. Description Venlafaxine is used to treat depression. It is also used to treat general anxiety disorder, social anxiety disorder, and panic disorder. Venlafaxine belongs to a group of medicines known as serotonin and norepinephrine reuptake inhibitors (SNRI). These medicines are thought to work by increasing the activity of a chemical called serotonin in the brain. This medicine is available. Detailed dosage guidelines and administration information for Effexor (venlafaxine hydrochloride). Includes dose adjustments, warnings and precautions. Effexor XR (venlafaxine) is used to treat major depressive disorder, anxiety, and panic disorder. Includes Effexor XR side effects, interactions and indications. Venlafaxine is used to treat major depressive disorder, anxiety, and panic disorder. Learn about side effects, interactions and indications.