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Candesartan is in a class of medications called angiotensin II receptor antagonists. It works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently. Candesartan is a prescription medication used to treat High Blood Pressure (hypertension) and Chronic Heart Failure. Learn about side effects, dosages, drug interactions, and more. Candesartan is administered clinically as the cyclohexyl 1- hydroxy ethyl carbonate ester, known as candesartan cilexetil. It is a cascading prodrug that is completely metabolised by esterases in the intestinal wall during absorption, releasing the active candesartan moiety. What is candesartan, and what is it used for? Candesartan cilexetil (candesartan) is a drug used for treating high blood pressure (hypertension). It is in a class of drugs called angiotensin receptor blockers (ARBs) which includes losartan (Cozaar), valsartan (Diovan), and irbesartan (Avapro). Lowering blood pressure can reduce the risk of strokes and heart attacks. Candesartan is also used to treat heart failure in adults and cut down on the number of hospital visits for heart problems. Candesartan is an angiotensin II receptor blocker (ARB). Candesartan cilexetil, a nonpeptide tetrazole derivative, is an angiotensin II receptor (AT1) antagonist (also referred to as an angiotensin II receptor blocker [ARB]). CANDESARTAN (kan des AR tan) treats high blood pressure and heart failure. It works by relaxing blood vessels, which decreases the amount of work the heart has to do. Candesartan is a type of medicine called an angiotensin receptor blocker (ARB). It helps manage high blood pressure (hypertension) and heart failure (where the heart cannot pump blood around the body properly). Find patient medical information for Candesartan (Atacand) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings What is candesartan? Candesartan is an angiotensin II receptor blocker (sometimes called an ARB). Candesartan is used to treat high blood pressure (hypertension) in adults and children who are at least 1 year old. Lowering blood pressure may lower your risk of a stroke or heart attack.