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Find patient medical information for Pioglitazone (Actos) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Find clinical guidance on Actos, including indications, dosing, safety, side effects and evidence-based insights for healthcare professionals. Actos (pioglitazone) is a drug prescribed for the treatment of type 2 diabetes. Side effects include sore throat, low blood sugar, sinusitis, and headache. Drug interactions, dosage, and pregnancy and breastfeeding safety information are provided. Actos (Pioglitazone Hydrochloride) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Pioglitazone (Actos) is an oral medication used to treat Type 2 diabetes in adults, along with diet and exercise. It's a thiazolidinedione, which works by helping your body respond better to insulin. This medication is taken by mouth once a day and is available in both brand and generic forms. A U.S. court has certified a nationwide class of third party payors in racketeering litigation tied to the diabetes drug Actos. The class includes U.S. insurers and other payors that reimbursed. Actos is an oral diabetes medicine that helps control blood sugar levels. Actos is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Actos (pioglitazone) is a prescription tablet that’s used to control blood sugar levels in type 2 diabetes. Learn about side effects, dosage, uses, and more. Pioglitazone (Actos) is an oral medication in the thiazolidinedione (TZD) class of drugs indicated for the treatment of type 2 diabetes. It helps insulin work better in muscle and fat cells and lowers blood glucose production in the liver. ACTOS therapy should not be initiated if the patient exhibits clinical evidence of active liver disease or serum transaminase levels (ALT) exceed 2.5 times the upper limit of normal (see.