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Arizona (16-14) will be trying to avoid their second consecutive series loss when they visit Wrigley Field on Saturday afternoon to face Chicago (19-12) in the second game of their three-game series at 2:20 PM. ET. Read on to find out which team picks up the win in this Diamondbacks vs. Cubs predict. Baseball USA MLB Chicago Cubs vs Arizona Diamondbacks live scores, head to head, schedule, predictions, lineups and stats Favourite Diamondbacks 16-16. @ Cubs 21-12 Arizona Diamondbacks vs. Chicago Cubs, pick, odds, best bet and betting preview for this MLB matchup on Saturday, May 2 Cubs -1.5 at +132 is the primary play, and the over 7.0 follows naturally when you consider what both starters bring to the table: volatile floors, an elite home offense, and a Gallen outing that could unravel if his shoulder limits his secondary offerings. Pregame analysis and predictions of the Arizona Diamondbacks vs. Chicago Cubs MLB game to be played on May 2, 2026 on ESPN. Before locking in your pick for the Arizona Diamondbacks vs. Chicago Cubs matchup, take a look at some key betting trends. Indeed, both teams have shown strong patterns in specific spots — and these stats could help uncover where the value lies on today’s MLB betting card. Chicago Cubs vs Arizona Diamondbacks picks and predictions for the 5/1/26 MLB game including lines and game spread by our Baseball experts.

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